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Figure S1 - p38 MAPK-Mediated Bmi-1 Down-Regulation and Defective Proliferation in ATM-Deficient Neural Stem Cells Can Be Restored by Akt Activation

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Bmi-1 downregulated in Atm-/- NSCs Atm+/+ and Atm-/- neurospheres were analyzed for phospho-p38, phospho-Akt, Bmi-1, and p21 by Immunofluorescence. Cells were counterstained by DAPI (4′-6-Diamidino-2-phenylindole), which identifies the nuclei of the NSCs. (DOC)

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2011-01-28
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