Cancer-associated fibroblasts (CAFs) in the tumor microenvironment are involved in the progression of esophageal squamous cell carcinoma (ESCC). We generated CAF-like cells by direct co-culture of hum

NIAID Data Ecosystem40

mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs.. Homo sapiens

SOX2转录因子

干细胞转录组学

Global transcriptome analysis reveals that SOX2 regulates a common group safeguarding stem cell identity in hESCs and hNPCs, and also distinct functional groups regulating diverse cell type dependent

NIAID Data Ecosystem20

SOX2 amplification status in sinonasal carcinomas.

鼻窦癌分子遗传学

SOX2转录因子

LLA: SOX2 low level amplification; HLA: SOX2 high level amplification; WT: SOX2 wildtype; SCC: squamous cell carcinoma; SNUC: sinonasal undifferentiated carcinoma; AD: adenocarcinoma; INVC: carcinoma

NIAID Data Ecosystem60

Genome-wide maps of SOX2 binding sites in lung cancer cells. Homo sapiens

癌症转录调控

SOX2转录因子

Discovery of SOX2 binding sites in lung cancer cells by CHIPseq and validate the target genes in two lung cancer cells by CHIP-QPCR. Overall design: Examination of SOX2 binding sites in lung cancer ce

NIAID Data Ecosystem20

SOX2 Drives Esophageal Squamous Carcinoma by Reprogramming Lipid Metabolism and Histone Acetylation Landscape

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