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Dual DNA demethylation mechanisms implement epigenetic memory driven by the pioneer factor PAX7

NIAID Data Ecosystem2026-05-02 收录

表观遗传记忆

DNA去甲基化机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280822 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-05-22

DNA去甲基化机制

细胞命运决定

Neurons harbor high levels of endogenous single strand DNA breaks (SSBs) that are targeted to neuronal enhancers and correlate with marks of DNA demethylation. To determine the source of SSBs at neuro

NIAID Data Ecosystem50

Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast [RNA-Seq]

干细胞重编程

表观遗传记忆

Reprogramming of ES cells towards the trophoblast lineage, and specifally into self-renewing TS cells, can seemingly be achieved by manipulation of transcription factors such as Cdx2 and Oct4, or modu

NIAID Data Ecosystem40

Epigenetic bookmarking of H2S exposure in Caenorhabditis elegans

表观遗传记忆

硫化氢应激反应

Physiological memories of environmental stress can serve to predict future environmental changes, allowing the organism to initiate protective mechanisms and survive. Although physiological memories,

NIAID Data Ecosystem20

Fam60a is a component of the mSin3A-HDAC transcriptional corepressor complex and inhibits Tet-mediated DNA demethylation

发育表观遗传调控

DNA去甲基化机制

Fam60a was identified as a highly expressed gene of unknown function in mouse embryonic stem cells. We have examined the role of Fam60a in mouse development. Most Fam60a mutant embryos manifest hypopl

NIAID Data Ecosystem40

Monotherapy of the DNA Hypomethylating Agent, NTX301 Targets Ovarian Cancer. Monotherapy of the DNA Hypomethylating Agent, NTX301 Targets Ovarian Cancer

卵巢癌药物靶向治疗

DNA去甲基化机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20