Herpes simplex virus 1 polymerase holoenzyme bound to DNA and DTTP in closed conformation
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Herpes simplex virus 1 polymerase holoenzyme bound to DNA and DTTP in closed conformation Descriptor: DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... Authors: Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. Deposit date: 2023-11-21 Release date: 2024-09-04 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance. Cell, 187, 2024
单纯疱疹病毒1型聚合酶全酶以闭合构象与DNA及脱氧胸苷三磷酸(DTTP)结合 描述项:DNA聚合酶(DNA polymerase)、DNA聚合酶持续合成因子(DNA polymerase processivity factor)、镁离子(MAGNESIUM ION)等 作者:Pan, J.、Abraham, J.、Coen, D.M.、Shankar, S.、Yang, P.、Hogle, J. 提交日期:2023-11-21 发布日期:2024-09-04 最后更新日期:2024-10-16 实验方法:电子显微镜(2.9 Å) 引用文献:《病毒DNA聚合酶结构揭示抗病毒药物耐药性机制》,《细胞(Cell)》,第187卷,2024年



