In this study, we identified and characterized a novel chromosomally-encoded class B metallo-β-lactamase (MBL) gene designated blaWUS-1 in a carbapenem-resistant isolate Myroides albus P34 isolated fr

NIAID Data Ecosystem10

Functional screening of transmembrane proteins identifies dolichyl pyrophosphate phosphatase CAX-4 as a key regulator of ergosterol biosynthesis and azole resistance in Neurospora crassa

真菌固醇生物合成调控

细菌耐药性机制

Ergosterol, a key lipid component of fungal membranes, has its homeostasis predominantly maintained through membrane-associated mechanisms, yet the role of the many transmembrane proteins in regulatin

NIAID Data Ecosystem00

Triclabendazole Resistant Fascioliasis

细菌耐药性机制

抗药性遗传标记识别

Fascioliasis, an important but neglected human fluke infection, is becoming resistant to triclabendazole, the only highly active medication available to treat humans. The mechanism of resistance is un

NIAID Data Ecosystem10

Crystal structure of MepR, a transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

蛋白质晶体

细菌耐药性机制

Crystal structure of MepR, a transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

NIAID Data Ecosystem00