Structure of the human TWIK-2 potassium channel in complex with pimozide
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Structure of the human TWIK-2 potassium channel in complex with pimozide Descriptor: 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1~{H}-benzimidazol-2-one, POTASSIUM ION, Potassium channel subfamily K member 6 Authors: Khanra, N.K, Long, S.B. Deposit date: 2024-12-06 Release date: 2025-04-23 Last modified: 2025-11-05 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Structure of the human TWIK-2 potassium channel and its inhibition by pimozide. Proc.Natl.Acad.Sci.USA, 122, 2025
与匹莫齐特(pimozide)结合的人类TWIK-2钾离子通道(TWIK-2 potassium channel)结构 描述符:3-[1-[4,4-双(4-氟苯基)丁基]哌啶-4-基]-1H-苯并咪唑-2-酮、钾离子(POTASSIUM ION)、钾通道K亚家族6号成员(Potassium channel subfamily K member 6) 作者:Khanra, N.K.、Long, S.B. 提交日期:2024-12-06 发布日期:2025-04-23 最后修改日期:2025-11-05 实验方法:电子显微镜(分辨率3.17埃) 引用文献:《人类TWIK-2钾离子通道的结构及其被匹莫齐特抑制的作用》,《美国国家科学院院刊(Proc. Natl. Acad. Sci. USA)》,122卷,2025年



