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Synthetic antagonist of a histone reader reveals and targets genes essential for inflammation

ChEBI2010-11-10 更新2026-07-21 收录

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炎症基因调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21910 数据链接链接失效反馈

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Synthetic antagonist of a histone reader reveals and targets genes essential for inflammation

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2010-11-10

LSD1酶活性抑制测定

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Inhibition of LSD1 enzymatic activity of SP-2577 and SP-2513 measured by Resorufin assay in a cell-free system.

NIAID Data Ecosystem80

Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation

移植物抗宿主病治疗

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Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvHD), primarily mediated through allo-reactive donor T cells in the donor stem cell graft. Enhancer of

NIAID Data Ecosystem40

Human Set Domain Bifurcated 1 (Setdb1), Tudor Domain; A Target Enabling Package

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Tudor结构域抑制剂

SETDB1 is a H3K9 methyltransferase involved in transcriptional silencing with a catalytic SET domain and a triple Tudor domain containing a methyl-lysine binding site. SGC Toronto previously solved th

Zenodo2020-09-20 更新30

Crystal Structure of KDM4D with GF026 ligand

蛋白质复合物结构解析

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Crystal Structure of KDM4D with GF026 ligand Descriptor: 1,2-ETHANEDIOL, 2-[2-(methylsulfonylamino)ethylamino]pyridine-4-carboxylic acid, CHLORIDE ION, ... Authors: Malecki, P.H, Link, A, Weiss, M.S,

Protein Data Bank Japan2024-01-17 更新60

Structure of CREBBP bromodomain with compound 2 bound

蛋白质-配体复合物结构

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Structure of CREBBP bromodomain with compound 2 bound Descriptor: CREB-binding protein, ~{N}-[3-(3-azanyl-5-methyl-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide Authors: Zh

Protein Data Bank Japan2024-01-24 更新30

Synthetic antagonist of a histone reader reveals and targets genes essential for inflammation

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