3D virtual Histopathology of Cardiac Tissue from Covid-19 Patients based on Phase-Contrast X-ray Tomography

X-ray phase-contrast tomography datasets of formalin fixed paraffin embedded unstained cardiac tissue from Covid-19 patients as well as from control tissue. For each group one overview scan of the entire biopsy (3.5mm cross section) from binning and stitching different tomograms (PB bin2, voxel size: 1.3µm) as well as the respective laboratory data (LJ, voxel size: 2µm, tissue masked) and a cone-beam zoom tomogram recorded with waveguide illumination (WG, voxel size: 159 nm) is uploaded. Further datasets can be provided on request. The data has been recorded at the institute for X-ray physics (Göttingen, Germany) and DESY at the GINIX instrument, beamline P10 of the PETRAIII storage ring (Hamburg, Germany). raw format, voxel numbers given in filename, single (32bit real)本数据集涵盖新型冠状病毒肺炎（COVID-19）患者与对照组的福尔马林固定石蜡包埋未染色心脏组织的X射线相位衬度断层扫描（X-ray phase-contrast tomography）数据。针对每组样本，均上传了三类数据：一是通过分箱与拼接不同断层扫描图像得到的完整活检组织全景扫描图像（横截面尺寸3.5mm，参数为PB bin2，体素尺寸1.3μm）；二是对应的实验室数据（LJ，体素尺寸2μm，已完成组织掩膜处理）；三是采用波导照明采集的锥束放大断层扫描图像（WG，体素尺寸159nm）。如需获取额外数据集，可提交申请。本数据分别采集于德国哥廷根X射线物理研究所，以及位于德国汉堡的PETRAIII储存环P10光束线GINIX仪器站（德国电子同步加速器DESY）。数据采用原始格式存储，文件名中包含体素数量信息，数据类型为单精度32位实数。