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Identification of p38 beta as a therapeutic target for the treatment of Sézary Syndrome

ChEBI2015-07-01 更新2026-07-12 收录

皮肤T细胞淋巴瘤

药物靶点发现

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-59179 数据链接链接失效反馈

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Identification of p38 beta as a therapeutic target for the treatment of Sézary Syndrome

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创建时间：

2015-07-01

分枝杆菌代谢途径

药物靶点发现

*ACP-FAS enzyme involved in the fifth reaction of the mycolic acid pathway ranks as the 38th unique hub in M. tuberculosis.

NIAID Data Ecosystem50

NGS-Raw-Data-SuFEx-2025.zip

化学文库筛选

药物靶点发现

This zip file contains the NGS raw data (fastq format, including R1 and R2) of the winner sequences identified by the SuFEx in vitro selection. After unzipping, in the folder or file names, SF, bFS an

DataCite Commons2025-05-15 更新40

Macrophage Migration Inhibitory Factor in Complex with a Naphthyridinone Inhibitor (4b)

结构生物学

药物靶点发现

Macrophage Migration Inhibitory Factor in Complex with a Naphthyridinone Inhibitor (4b) Descriptor: Macrophage migration inhibitory factor, SULFATE ION, {2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triaz

Protein Data Bank Japan2023-10-04 更新30

Sézary Syndrome Originates from Heavily Mutated Hematopoietic Progenitors

血液肿瘤基因组学

皮肤T细胞淋巴瘤

The pathogenesis of cutaneous T cell lymphoma (CTCL) remains unclear. To study the malignant transformation of CTCL, we collected matched hematopoietic stem cell (HSC) extracts from bone marrow, CD4+C

NIAID Data Ecosystem40

Catalytic Domain of Human Calpain 8

蛋白酶结构解析

药物靶点发现

Catalytic Domain of Human Calpain 8 Descriptor: CALCIUM ION, Calpain-8, Leupeptin Inhibitor Authors: Davis, T.L, Paramanathan, R, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith,

Protein Data Bank Japan2024-10-30 更新30

Identification of p38 beta as a therapeutic target for the treatment of Sézary Syndrome

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