The pattern of functional autoantibodies in patients with unclassified, Lewy body, vascular and Alzheimer’s dementia.

Serum positivity and negativity are demonstrated for autoantibodies directed against α1-adrenergic (α1-AABs), β2-adrenergic (β2-AABs) and endothelin A receptors (ETA-AABs); a score was calculated for the integrated activity assessment of the three autoantibodies directed against G-protein coupled receptors (GPCR-AABs). For the score calculation, the GPCR-AAB activities were summarized based on: 0 point = GPCR-AAB level LLD < cut-off; 2 points = GPCR-AAB level > cut-off.