Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)

Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... Authors: Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. Deposit date: 2017-04-28 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.05 Å) Cite: CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018

Kaiso（ZBTB33）锌指DNA结合结构域（zinc finger DNA binding domain）与类似Kaiso特异性结合序列（Kaiso Binding Sequence，KBS）的半CpG甲基化DNA形成复合物。
描述：氯离子、DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3')、DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3')……
作者：Nikolova, E.N.、Stanfield, R.L.、Martinez-Yamout, M.A.、Dyson, H.J.、Wright, P.E.
沉积日期：2017-04-28
发布日期：2018-04-04
最后修改日期：2023-10-04
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.05埃（Å）
引用文献：CH···O氢键介导锌指蛋白Kaiso对甲基化CpG位点的高度特异性识别。《生物化学（Biochemistry）》，第57卷，2018年