Molecular motors are required to establish anterior-posterior dendritic patterning.
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https://figshare.com/articles/dataset/_Molecular_motors_are_required_to_establish_anterior_posterior_dendritic_patterning_/1618364
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(A) Schematic of the directionality of motor movement based on MT polarity in a wild-type PVD dendrite. (B-E) Representative images of PVD::GFP in various genotypes, as indicated on each micrograph. Insets are schematics of MT polarity in the primary dendrite. (F) Quantification of subcellular distribution of branch complexity in wild-type, unc-116(e2310), and dhc-1(or195ts) animals. (G) Quantification of subcellular distribution of branch complexity in unc-116(e2310), rab-10(ok1494), and unc-116(e2310);rab-10(ok1494) double mutant animals. Scale bars represent 20 μm. Error bars represent SEM. * p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 by 2-way ANOVA with Tukey’s multiple comparisons test. N>5 for all genotypes.
创建时间:
2015-12-03



