Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 8-oxo-dGTP determined using a crystal obtained under microgravity

Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 8-oxo-dGTP determined using a crystal obtained under microgravity Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... Authors: Nakamura, T, Yamagata, Y. Deposit date: 2018-10-12 Release date: 2019-02-20 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.04 Å) Cite: X-ray Structure Analysis of Human Oxidized Nucleotide Hydrolase MTH1 using Crystals Obtained under Microgravity. Int. J. Microgravity Sci. Appl., 36, 2019

人源MTH1（G2K/C87A/C104S突变体）与8-氧代-2'-脱氧鸟苷-5'-三磷酸（8-oxo-dGTP）复合物的晶体结构，该结构通过微重力环境下获得的晶体解析得到。
描述符：7,8-二氢-8-氧代鸟嘌呤三磷酸酶 (7,8-dihydro-8-oxoguanine triphosphatase)、8-氧代-2'-脱氧鸟苷-5'-三磷酸 (8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE)、甘油 (GLYCEROL) 等。
作者：Nakamura T、Yamagata Y
入库日期：2018-10-12
发布日期：2019-02-20
最后更新：2024-03-27
解析方法：X射线衍射 (X-RAY DIFFRACTION)，分辨率1.04 Å
引用文献：《基于微重力晶体的人源氧化核苷酸水解酶MTH1的X射线结构解析》，《国际微重力科学与应用杂志（Int. J. Microgravity Sci. Appl.）》，2019年，第36卷。