mRNA sequencing of WNT conditioned USH1C patient-derived fibroblasts
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https://www.ncbi.nlm.nih.gov/sra/SRP418047
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资源简介：
USH1C patient-derived dermal fibroblasts cells, have been recently established as a cellular model of USH disease for translational research (Grotz et al., 2022, Nagel-Wolfrum et al., 2022). In human dermal fibroblasts, Wnt signaling is important for the cellular function related to hair follicle development, regional cell identity, and wound healing, and its dysregulation can lead to skin fibrosis or wound healing defects (Enzo et al., 2015, Griffin et al., 2022). We cultivated dermal fibroblasts from a clinically characterized USH1C patient with USH1CR31*/80Pfs*69 and a healthy control individual (healthy fibroblasts) in control medium and Wnt conditioned medium (WMS), respectively, and examined their transcriptomes by RNAseq.
创建时间：
2023-02-02
