Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanism
BackgroundIn response to liver injury, hepatic stellate cell (HSC) activation causes excessive liver fibrosis. Here we show that activation of RSK and phosphorylation of C/EBPβ on Thr217 in activated
To investigated the role of CD73 in liver fibrosis, RNA-sequencing of fibrotic liver tissues from CCL4-induced mice were performed. Three groups (three mice for each group) were included in this study
Structure of NNQQNY as an insert in T7 endonuclease I Descriptor: Endonuclease I Authors: Guo, Z, Eisenberg, D. Deposit date: 2008-02-19 Release date: 2008-07-22 Last modified: 2023-08-30 Method: X-RA
SCN5A coding for sodium channels in the heart and its reduced activity implicated various biological processes including fibrogenesis. However, the mechanistic interplay between loss of SCN5A activit
