Dataset on cadaveric human abdominal aorta aneurysm biomechanics (uniaxial) and histology

The present dataset is a collection of information about the biomechanical behavior and histological characterization of abdominal aortic aneurysms (AAA) harvested during the autopsy procedure. The primary hypothesis of the present research is: Do cadaveric AAA walls, when previously stressed by inflation, conserve significant resistance against tearing comparable to no previously stressed aortas described in the literature? Eight AAAs (6 fusiform and two saccular) were carefully dissected and had their branches ligated with cotton or prolene sutures. Each specimen has been submitted to intraluminal pressurization, up to the rupture of their wall. This pressurization was made through the inflation of an air balloon inside the specimens up to their rupture. Four samples were collected from each specimen (two from each side of the rupture border and two control samples, one from a proximal and a second from a distal no dilated region of the vessel) for uniaxial tensile tests and histological analysis. The uniaxial tensile test utilized the INSTRON SPEC 2200 device and was coordinated by INSPEC software and SERIES IX software. The variables measured through this test were failure stress, failure tension, and failure strain. Each sample test generated a chart representing the relationship between stress and strain. The histological analysis included Picrosirius (collagen fibers) and Voerhoeff (elastic fibers) stains. Unfortunately, some samples were lost, especially during histological processing. A quantitative analysis (collagen and elastic fibers) was made using the software Pannoramic Viewer/Case Viewer.1 Notable findings: Even after being stretched/stressed up to their rupture, the specimens conserved uniaxial biomechanical properties comparable to AAA and normal aorta samples previously described in the literature by Monteiro e Nynomiya respectively.2,3 DATA DESCRIPTION: a) Biomechanical Data: For each valid sample test, three documents are generated: 1. Stress X strain chart 2. Table (excel file containing all the values related to the stress X strain chart 3. A report from the Biomechanical test software containing details of the test All charts contain a notification in their left upper corner about the failure stress, strain and tension of each sample. It is important to highlight here that some samples did not produce valid biomechanical tests, so they do not have their results included here. b) Histological Data: The percentage of coverage of collagen fibers and elastin fibers is expressed in table I in decimal numbers (for example, 0.36 = 36%). Similarly to the sampling for biomechanical tests, four samples were harvested from each aorta, when it was feasible. Each case has a "histology files" folder containing the images (.JPG) used for the analysis. Ps.: Case C samples (histology) were damaged during processing (therefore they were not included in the present dataset).本数据集收录了尸检中获取的腹主动脉瘤（abdominal aortic aneurysms, AAA）的生物力学行为与组织学特征相关信息。 本研究的核心假设为：经预扩张应力作用的尸体腹主动脉瘤壁，是否仍能保持与文献中未受预应力作用的主动脉相当的抗撕裂性能？ 本研究共获取8例腹主动脉瘤标本（6例梭形，2例囊状），经精细解剖后使用棉线或聚丙烯缝线（Prolene）结扎其分支血管。 每份标本均接受腔内加压处理，直至管壁破裂。加压方式为向标本内置入气囊充气直至破裂。从每份标本中采集4份样本：破裂边缘两侧各2份，以及血管近端无扩张区和远端无扩张区各1份作为对照样本，用于单轴拉伸试验（uniaxial tensile test）与组织学分析。 单轴拉伸试验使用INSTRON SPEC 2200设备完成，并由INSPEC软件与SERIES IX软件协同控制。该试验测得的变量包括破坏应力、破坏张力与破坏应变。每份样本的测试均生成一张表征应力-应变关系的图表。组织学分析采用天狼星红染色（Picrosirius stain，用于显示胶原纤维）与弗尔霍夫染色（Voerhoeff stain，用于显示弹性纤维）。遗憾的是，部分样本在组织学处理过程中丢失。使用Pannoramic Viewer/Case Viewer软件完成了胶原纤维与弹性纤维的定量分析。 重要发现：即便经拉伸/应力作用直至破裂，这些标本仍保留了与文献中Monteiro和Nynomiya分别报道的腹主动脉瘤及正常主动脉样本相当的单轴生物力学性能[2,3]。 数据说明： a) 生物力学数据： 对于每份有效的测试样本，将生成三类文档： 1. 应力-应变曲线图 2. 数据表（Excel文件，包含与应力-应变曲线图相关的全部数值） 3. 生物力学测试软件生成的试验详情报告 所有图表的左上角均标注有对应样本的破坏应力、应变与张力信息。 需特别说明的是，部分样本未获得有效的生物力学测试结果，因此未将其结果纳入本数据集。 b) 组织学数据： 胶原纤维与弹性纤维的覆盖率以小数形式在表I中呈现（例如，0.36即代表36%）。与生物力学测试采样规则一致，若条件允许，每份主动脉标本均采集4份样本。每个病例均配有“组织学文件”文件夹，内含用于分析的图像（.JPEG格式）。 注：C组样本（组织学样本）在处理过程中受损，因此未纳入本数据集。