Additional file 1 of Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons

Additional file 1. Cuffdiff2 differential expression data. Tabs are for each injury condition and time point vs. their relevant controls (N = 3 biological replicates, each). Tabs PW1–3) Tadpole spinal cord injury (SCI) hindbrain vs. age-matched, unoperated control hindbrain at 3 days, 1 week, and 3 weeks, respectively; PW4–6) Juvenile frog SCI hindbrain at 3 days, 1 week, and 3 weeks vs. unoperated control hindbrain; PW7–9) juvenile frog optic nerve crush (ONC) eye vs. the contralateral unoperated eye at 3 days, 11 days, and 3 weeks, respectively. Abbreviations: chr, chromosome; cntrl, control; FPKM, fragments per kilobase of transcript per million mapped reads; ONC, optic nerve crush; p, the calculated probability for a single given gene that the observed difference represented no change in expression (i.e., log2(fold change) = 0); q, false discovery rate-adjusted (FDR) p-value [14]; significant, “yes” if q附加文件1：Cuffdiff2差异表达分析数据。 各工作表对应一种损伤条件及时间点与其相应对照组的比较（每组均设置3次生物学重复）。 工作表PW1~3分别对应：蝌蚪脊髓损伤（spinal cord injury, SCI）后脑与同龄未手术对照后脑在损伤后3天、1周及3周的比较； 工作表PW4~6对应：幼蛙脊髓损伤（SCI）后脑在损伤后3天、1周及3周与未手术对照后脑的比较； 工作表PW7~9分别对应：幼蛙视神经钳夹（optic nerve crush, ONC）眼部在损伤后3天、11天及3周与对侧未手术眼部的比较。 术语缩写说明：chr（chromosome，染色体）；cntrl（control，对照）；FPKM（fragments per kilobase of transcript per million mapped reads，每百万比对片段中每千碱基转录本的片段数）；p值：单个基因观测表达差异无变化的计算概率（即log₂(折叠变化)=0）；q值：经错误发现率（FDR）校正的p值[14]；significant：若q值满足要求则标注为“是”