FLI1 and GATA1 govern TLN1 transcription: new insights into FLI1-related platelet disorders - Bioinformatics resources and Docker environments

This repository provides Docker containers designed to reproduce the analyses presented in Gabinaud et al. (2025), along with selected intermediate files. Detailed instructions for reproducing the analysis are available on github (https://github.com/poggiteam/FLI1_2021) and raw data and other intermediate files are available in GEO/SRA (GSE273210 / SRP522475) for the sc-RNAseq. This Zenodo hosts the following resources : Docker and Singularity images used for the analysis (cellranger5.img, citeseq-count1.4.3.img, souporcell_latest.sif and Seurat4.tar) Human reference transcriptome (refdata-gex-GRCh38-2020-A.tar.gz) Files generated by .Rmd scripts (FLI_J5_regress_no_analysis.rds, FLI_J11_regress_no_analysis.rds, 17_11_22_FLI1_manip2_ctrl_filtered_regress_no_analysis.rds, 17_11_22_FLI1_manip2_pat_filtered_regress_no_analysis.rds, 18_11_22_FLI1_manip2_combined_regress_no_analysis.rds)