Targeting the chromatin-binding of XPO1 disrupts NFAT and T cell activation

NIAID Data Ecosystem2026-05-01 收录

细胞激活机制

XPO1功能研究

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE228212 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-05-02

Differential Expressions of miRNAs in resting and activated human in vitro-differentiated NK cells. Homo sapiens

细胞miRNA表达谱

细胞激活机制

To investigate miRNA expressions of miRNA upon activation. Overall design: In vitro-differentiated human NK cells were freshly incubated in the presence of IL15 after 24h deprivation of IL-15. The cel

NIAID Data Ecosystem90

resting and IL2 activated human natural killer cells

细胞激活机制

时序基因表达分析

The aim of the study was to investigate the activation of human NK cells by IL2 through analyzing the global gene expression at different time points (0, 2, 8 and 24 hours) after culture with the cyto

NIAID Data Ecosystem40

Salt augments macrophage-driven host defense in the skin. Salt augments macrophage-driven host defense in the skin

皮肤抗菌免疫

细胞激活机制

Immune cells regulate a hypertonic microenvironment in the skin; however, possible functions of increased skin Na+ concentrations are unknown. We found that Na+ accumulated at the site of bacterial sk

NIAID Data Ecosystem30

Correlates of macrophage and monocyte activation.

细胞激活机制

感染免疫学

Spearman's rank correlation ‘rs’ value is given; *p<0.05, ** p<0.01 and ***p<0.001, ‘–’ denotes inverse associations and ns = no significant correlation. Variables that are not shown displayed no co

NIAID Data Ecosystem60

Transcriptomic_analysis_of_naive_and_activated_CD8_T_cells. Transcriptomic_analysis_of_naive_and_activated_CD8_T_cells

免疫细胞转录组学

细胞激活机制

RNA was isolated from purified CD8 T cells obtained from C57BL/6 wildtype mice (n=10). The intention of the study is to determine the differences in gene expression between naive and activated CD8 T c

NIAID Data Ecosystem30

Targeting the chromatin-binding of XPO1 disrupts NFAT and T cell activation

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