Microtubule-associated kinesin-1 tail complex bound to ADP, two-headed state

Microtubule-associated kinesin-1 tail complex bound to ADP, two-headed state Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Atherton, J, Chegkazi, M.S, Steiner, R.A. Deposit date: 2023-12-19 Release date: 2024-11-20 Last modified: 2025-07-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail. Nat Commun, 16, 2025结合二磷酸腺苷（ADP）的微管相关驱动蛋白-1尾部复合物（双头状态） 描述项：腺苷-5'-二磷酸、鸟苷-5'-二磷酸、鸟苷-5'-三磷酸…… 作者：Atherton J、Chegkazi M S、Steiner R A 提交日期：2023-12-19 发布日期：2024-11-20 最后修改日期：2025-07-16 实验方法：电子显微镜（分辨率3.6埃） 引用文献：微管结合会诱导驱动蛋白-1形成不含镁的载脂蛋白样ADP预释放构象，该构象不受其自身抑制性尾部的影响。《自然-通讯》（Nat Commun），16卷，2025年