Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis

This dataset contains the results of 2 related analyses, described in "Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis" (European Heart Journal Supplements, OUP). Link to the article: https://www.hal.inserm.fr/inserm-02310241 1) In the directory "miRNAs_MARTHA_GWAS" : GWAS summary statistics for 162 circulating miRNAs in 344 VTE patients from the MARTHA cohort. Header for each summary file: Trait: miRNA id<br> chr: Chromosome<br> pos.hg19: Position of the variant in hg19/GRCh37 coordinates<br> SNP: rsid<br> A1: Reference allele on the forward strand<br> A2: Alternate allele on the forward strand<br> freq_A1: Frequency of reference allele<br> rsqr: Imputation quality defined by MACH<br> beta_A1: Estimated effect size (beta regression coefficient) of reference allele<br> se_A1: Estimated standard error of beta<br> p: p-value (significance of estimated beta)<br> z.score: Z-score 2) In the directory "meta_analysis": Random effect meta-analysis combining the results of our GWAS on the MARTHA cohort, and the results from a similar analysis conducted by Nikpay et al. (doi: 10.1093/cvr/cvz030). Summary statistics of 142 microRNAs, common to both datasets, were processed (and combine 1054 samples). Header for each summary file: chr: Chromosome<br> pos.hg19: Position of the variant in hg19/GRCh37 coordinates<br> SNP: rsid<br> A1: Reference allele on the forward strand<br> A2: Alternate allele on the forward strand<br> N: Sample size<br> Q: Cochran's heterogeneity statistic<br> Q.p: p-value of Cochran's Q<br> beta_A1: Estimated effect size (beta regression coefficient) of reference allele<br> se_A1: Estimated standard error of beta<br> p: p-value (significance of estimated beta)