characterization of mesenchymal stem cell derived from N1-12 and 201B7 via mesoderm and neuroepithelia

We established new methods for differentiating hiPSCs into MSCs via mesoderm-like and neuroepithelium-like cells. We named MSCs via mesoderm-like as PSP-MSC, and MSCs via neuroepithelium-like cells. To further characterize our PSP-MSCs and RA-Pα-MSCs, we compared their genome-wide expression patterns with those of human iPSCs and BM-MSCs (PRC-010; Bay bioscience) using DNA microarrays. Gene expression of N1-12, BM-MSC, MSC derived from N1-12 and 201B7 via mesoderm, MSC derived from N1-12 and 201B7 via neuroepithelia by Affymetrix Human Genome U133 Plus 2.0 Array