Density measurements of different receptors for Area PFm (IPL) [human, v1.0]
收藏DataCite Commons2021-07-20 更新2025-04-15 收录
下载链接：
https://kg.ebrains.eu/search/instances/Dataset/8b7c06e5693c323e4524a195f9ca4d19
下载链接
链接失效反馈官方服务：
资源简介：
This dataset contains the densities (in fmol/mg protein) of receptors for classical neurotransmitters in Area PFm (IPL) obtained by means of quantitative _in vitro_ autoradiography. The receptor densities are visualized as _fingerprints_ (**fp**), which provide the mean density and standard deviation for each of the analyzed receptor types, averaged across samples. Overview of available measurements [ **receptor** \| **_neurotransmitter_** \| _labeling agent_ ]: **AMPA** \| **_glutamate_** \| _[<sup>3</sup>H]AMPA_ **kainate** \| **_glutamate_** \| _[<sup>3</sup>H]kainate_ **NMDA** \| **_glutamate_** \| _[<sup>3</sup>H]MK-801_ **mGluR2/3** \| **_glutamate_** \| _[<sup>3</sup>H]LY341495_ **GABA<sub>A</sub>** \| **_GABA_** \| _[<sup>3</sup>H]muscimol_ **GABA<sub>B</sub>** \| **_GABA_** \| _[<sup>3</sup>H]CGP54626_ **GABA<sub>A</sub>/BZ** \| **_GABA_** \| _[<sup>3</sup>H]flumazenil_ **muscarinic M<sub>1</sub>** \| **_acetylcholine_** \| _[<sup>3</sup>H]pirenzepine_ **muscarinic M<sub>2</sub>** \| **_acetylcholine_** \| _[<sup>3</sup>H]oxotremorine-M_ **muscarinic M<sub>3</sub>** \| **_acetylcholine_** \| _[<sup>3</sup>H]4-DAMP_ **nicotinic α<sub>4</sub>β<sub>2</sub>** \| **_acetylcholine_** \| _[<sup>3</sup>H]epibatidine_ **α<sub>1</sub>** \| **_noradrenalin/norepinephrine_** \| _[<sup>3</sup>H]prazosin_ **α<sub>2</sub>** \| **_noradrenalin/norepinephrine_** \| _[<sup>3</sup>H]UK-14,304_ **5-HT<sub>1A</sub>** \| **_serotonin_** \| _[<sup>3</sup>H]8-OH-DPAT_ **5-HT<sub>2</sub>** \| **_serotonin_** \| _[<sup>3</sup>H]ketanserin_ **D<sub>1</sub>** \| **_dopamine_** \| _[<sup>3</sup>H]SCH23390_ For exemplary samples, we also provide laminar _profiles_ (**pr**) and/or color-coded laminar _autoradiography_ images (**ar**). The density profiles provide, for a single tissue sample, an exemplary density distribution for a single receptor from the pial surface to the border between layer VI and the white matter. The autoradiography images show an exemplary density distribution of a single receptor for one laminar cross-section in a single tissue sample. Information on the used tissue samples and corresponding subjects for the receptor fingerprints, profiles and autoradiographs as well as a list of analyzed receptors accompanies the provided dataset. **For methodological details, see:** Zilles, K. et al. (2002). Quantitative analysis of cyto- and receptorarchitecture of the human brain, pp. 573-602. In: Brain Mapping: The Methods, 2nd edition (A.W. Toga and J.C. Mazziotta, eds.). San Diego, Academic Press. Palomero-Gallagher N, Zilles K. (2018) Cyto- and receptorarchitectonic mapping of the human brain. In: Handbook of Clinical Neurology 150: 355-387
提供机构：
Human Brain Project Neuroinformatics Platform
创建时间：
2018-10-25
