Glioma Image Segmentation for Radiotherapy: RT targets, barriers to cancer spread, and organs at risk (GLIS-RT)

The imaging data consists of 230 cases of glioblastoma and low-grade glioma patients treated with surgery and adjuvant radiotherapy at Massachusetts General Hospital. The patients underwent routine post-surgical MRI examination by acquiring two MR sequences, contrast enhanced 3D-T1 and 2D multislice-T2 FLAIR required to define target volumes for radiotherapy treatment. CT scans were acquired after diagnostic imaging to use in radiotherapy treatment planning. All cases in the image set are provided with the radiotherapy targets, gross tumor volume (GTV) and clinical target volume (CTV) manually delineated by the treating radiation oncologist. The subset of these 230 cases consisting of 75 cases was used for the International Challenge “Anatomical Brain Barriers to Cancer Spread: Segmentation from CT and MR Images”, ABCs, organized in conjunction with the MICCAI 2020 conference (https://abcs.mgh.harvard.edu). For these cases, manual delineations are provided including 17 structures: falx cerebri, tentorium cerebelli, transverse and sagittal brain sinuses, ventricles, cerebellum, brainstem, optic chiasm, optic nerves, eyes, cochlea, and lacrimal glands.

本影像数据集包含麻省总医院（Massachusetts General Hospital）收治的230例胶质母细胞瘤（glioblastoma）与低级别胶质瘤（low-grade glioma）患者病例，所有患者均接受手术治疗联合辅助放疗。
患者术后接受常规磁共振成像（Magnetic Resonance Imaging, MRI）检查，采集两种磁共振序列以确定放疗靶区：增强三维T1加权像（contrast enhanced 3D-T1）与二维多层T2加权液体衰减反转恢复序列（2D multislice-T2 FLAIR, FLAIR）。
诊断成像完成后采集计算机断层扫描（Computed Tomography, CT）扫描图像，用于放疗计划制定。
本数据集的所有病例均附带由接诊放射肿瘤医师手动勾画的放疗靶区：大体肿瘤体积（gross tumor volume, GTV）与临床靶区（clinical target volume, CTV）。
其中75例作为该230例病例的子集，被用于与MICCAI 2020会议联合举办的国际挑战赛"肿瘤扩散的脑部解剖屏障：CT与MR图像分割"（ABCs），挑战赛官方网址为https://abcs.mgh.harvard.edu。
针对该75例病例，数据集提供17种结构的手动勾画结果：大脑镰（falx cerebri）、小脑幕（tentorium cerebelli）、大脑横窦与矢状窦（transverse and sagittal brain sinuses）、脑室、小脑、脑干、视交叉（optic chiasm）、视神经、眼球、耳蜗及泪腺。