ZBTB7A prevents RUNX1-RUNX1T1 dependent clonal expansion of human hematopoietic progenitor cells
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https://www.ncbi.nlm.nih.gov/sra/SRP230200
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资源简介：
ZBTB7A is frequently mutated in acute myeloid leukemia (AML) with t(8;21) translocation. However, the oncogenic collaboration between mutated ZBTB7A and the RUNX1-RUNX1T1 fusion gene in AML t(8;21) remains unclear. Here, we investigate the role of ZBTB7A and its mutations in the context of normal and malignant hematopoiesis. Overall design: RNA-seq of control and ZBTB7A in K562 cell lines.
创建时间：
2020-04-10
