Data for: Anti-inflammatory Potential of South African Medicinal Plants used in the Treatment of Sexually Transmitted Infections

The dataset represents biological assays, conducted to determine the inhibitory activity of extracts from 12 South African medicinal plants on selected inflammatory enzymes, as well as their ability to reduce nitric oxide production, in response to inflammatory stimulation with lipopolysaccharide (LPS) in macrophage cells. The viability of macrophage cells and confirmation of cytotoxicity status of active extracts was done on Vero cells using the MTT assay. Results of antioxidant scavenging capacity of extracts are also presented. NMR spectroscopic data are presented as mestronova files while the amount of phenolic and flavonoid contents in the extracts were determined from a calibration curve of gallic acid and quercetin as shown in the data set. All experiments were carried out according to standard protocols as described in the full article.本数据集收录了针对12种南非药用植物提取物的多类生物学活性检测实验：其一为测定提取物对选定炎性酶的抑制活性，以及在脂多糖（lipopolysaccharide, LPS）刺激巨噬细胞（macrophage cells）产生炎症反应的情况下，提取物减少一氧化氮生成的能力；其二为采用MTT法（MTT assay）在Vero细胞（Vero cells）上开展巨噬细胞存活率检测，并确认活性提取物的细胞毒性状态。本数据集同时收录了提取物的抗氧化清除能力检测结果。核磁共振波谱（NMR）数据以MestReNova文件格式提供；提取物中酚类与黄酮类物质的含量，则通过数据集所示的没食子酸（gallic acid）与槲皮素（quercetin）标准曲线进行定量。所有实验均严格遵循正文中描述的标准实验规程完成。