Single-cell genome and transcriptome sequencing of Pelomyxa schiedti

We sequenced the genome and transcriptome of Pelomyxa schiedti, a free-living anaerobic amoeba of the Archamoebae group, and its symbionts. The main aim was to reconstruct the metabolism of its anaerobic mitochondrial-related organelle (MRO) and peroxisome, and to reveal metabolic connections between the amoeba and its endosymbionts.