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B16-huCD20 tumors treated with 177Lu-TRT were subjected to multiplex analysis to study the tumor immune signature.

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199624
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Targeted gene expression on 9 B16-huCD20 Melanoma tumor samples treated with 177Lu-radiolabed sdAbs using the murine panCancer Immune panel (NanoString Technologies) In the study presented here, 9 mice were inoculated s.c. with 100.000 B16-huCD20 tumorcells and were treated 3, 9 and 14 days after inoculation with 177Lu-labeled sdAbs (3 low dose TRT, 3 high dose TRT and 3 control conditions) were used to acquire expression profiles of a total of 770 genes, leading to assessment of alterations in the tumor microenvironment
创建时间:
2022-05-10
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