4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects

4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects Descriptor: 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, CELL DIVISION PROTEIN KINASE 2 Authors: Krystof, V, Cankar, P, Frysova, I, Slouka, J, Kontopidis, G, Dzubak, P, Hajduch, M, Deazevedo, W.F, Paprskarova, M, Orsag, M, Rolcik, J, Latr, A, Fischer, P.M, Strnad, M. Deposit date: 2006-05-02 Release date: 2006-11-01 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: 4-Arylazo-3,5-Diamino-1H-Pyrazole Cdk Inhibitors: Sar Study, Crystal Structure in Complex with Cdk2, Selectivity, and Cellular Effects J.Med.Chem., 49, 2006

4-芳基偶氮-3,5-二氨基-1H-吡唑类细胞周期蛋白依赖性激酶（CDK）抑制剂：构效关系研究、与CDK2复合物的晶体结构、选择性及细胞效应
描述物：4-[(E)-(3,5-二氨基-1H-吡唑-4-基)二氮烯基]苯酚、细胞分裂蛋白激酶2（CDK2）
作者：Krystof, V、Cankar, P、Frysova, I、Slouka, J、Kontopidis, G、Dzubak, P、Hajduch, M、Deazevedo, W.F、Paprskarova, M、Orsag, M、Rolcik, J、Latr, A、Fischer, P.M、Strnad, M
入库日期：2006-05-02
发布日期：2006-11-01
最后修改日期：2025-10-01
测试方法：X射线衍射（分辨率1.8埃）
引用文献：《4-芳基偶氮-3,5-二氨基-1H-吡唑类CDK抑制剂：构效关系研究、与CDK2复合物的晶体结构、选择性及细胞效应》，《药物化学杂志》，49卷，2006年