Crystal Structure of human PI3Kgamma complexed with AS605240
收藏Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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Crystal Structure of human PI3Kgamma complexed with AS605240 Descriptor: (5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform Authors: Camps, M, Ruckle, T, Ji, H, Ardissone, V, Rintelen, F, Shaw, J, Ferrandi, C, Chabert, C, Gillieron, C, Francon, B, Martin, T, Gretener, D, Perrin, D, Leroy, D, Vitte, P.-A, Hirsch, E, Wymann, M.P, Cirillo, R, Schwarz, M.K, Rommel, C. Deposit date: 2005-07-01 Release date: 2005-09-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis NAT.MED. (N.Y.), 11, 2005
创建时间：
2005-07-01
