A summary of uncontrolled studies on the efficacy and safety of chemoradiation with TMZ for GBMs in the elderly.

RT = radiotherapy; SRS = stereotactic radiosurgery; TMZ = temozolomide; either TMZ = either sequential or concurrent TMZ; Sx = surgery; CR = complete resection; PFS = progression free survival; OS = overall survival; CI = confidential interval; HAE = hematological adverse event; yrs = years; mths = months; nr = not reported.apatients aged bmean but not median.cthe whole cohort.dThe Eastern Cooperative Oncology Group (ECOG) performance status.