Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.

Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. Deposit date: 2022-10-18 Release date: 2024-05-01 Last modified: 2025-07-16 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024

人类成熟pre-B状态外显子界定剪接体的冷冻电镜（Cryo-EM）结构。描述项：116 kDa U5小核核糖核蛋白组分、5'-三磷酸鸟苷（GUANOSINE-5'-TRIPHOSPHATE）、肌醇六磷酸（INOSITOL HEXAKISPHOSPHATE）等……作者：Zhang W、Zhan X、Zhang X、Lei J、Yan C、Shi Y。提交日期：2022-10-18；发布日期：2024-05-01；最后修改日期：2025-07-16。方法：电子显微镜（分辨率3.25 Å）。引用文献：《激活前人类外显子界定剪接体的结构解析》，《细胞研究》（Cell Res.），第34卷，2024年。