Structural studies on Mycobacterial NudC reveal a class of zinc independent NADH pyrophosphatase
收藏科学数据银行2024-12-09 更新2026-04-23 收录
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资源简介：
Non-tuberculous mycobacteria (NTM) have emerged as an increasing threat to public health, due to the extreme antibiotic resistance. NADH pyrophosphatase (NudC) was proposed involving in mycobacterial resistance to the first line anti-tubercular drug isoniazid (INH) or its analog ethionamide (ETH), by hydrolyzing their NAD modified active forms (NAD-INH and NAD-ETH).
提供机构：
Jinsong Liu*; Yulong Zhang; Huaiwei Ding; Zhaojian Sun; Yirong Sun; Jinxin Xu*; Xiaoan Du; Yujian Wu; Guangzhou Institutes of Biomedicine and Health; Lingyu Meng
创建时间：
2024-12-03
