Afatinib is a pan-HER inhibitor that improved progression-free-survival (PFS) in recurrent HNSCC versus methotrexate: median PFS 2.6 versus 1.7 months (LUX H&N 1 trial). This study is a translational
The purpose of this study is to evaluate, in terms of overall survival, the benefit of monoclonal antibodies in the start time of the diagnosis of advanced disease or administer a deferred basis after
Lumbar spine MRI and chest CT were taken. A, before initiation of treatment with imatinib. B, after 4 months treatment with imatinib. C, after further 2 months treatment with imatinib and 3 months tre