Patient characteristics according to baseline eGFR and decline of eGFR.

Patients have been assigned to two groups by the median of eGFR at baseline (99.19 ml/min/1.73 m2.) and in contrast by the median of eGFR decline (or change, respectively) between baseline and the 3.5 year follow up (ΔeGFR; 2.39 ml/min/1.73 m2). All data are given as means ± standard deviation or percentages and p-values each express the difference between respective two groups. CAD is defined by angiographically determined coronary artery stenoses with lumen narrowing ≥50%. CAD denotes coronary artery disease, BMI body mass index, T2DM type 2 diabetes mellitus, CRP C-reactive protein, LDL low density lipoprotein, HDL high density lipoprotein, ACE angiotensin converting enzyme, and AT-2 angiotensin 2. Patient characteristics according to baseline eGFR and decline of eGFR.