MAPK docking pattern hits on human proteins.

Using each of the MAPK docking site patterns, we scanned phosphorylated substrates in dbPTM. We show the number of substrates with pattern matches as well as results for ERK1/2 substrates. We used Fisher's test to calculate a p-value for the enrichment of pattern hits on ERK1/2 substrates compared to all other phosphorylated proteins. The standard docking site patterns, Da and Db, were not enriched on ERK1/2 substrates, but the union of these patterns was enriched. Dc, but not Dd, was found to be enriched on ERK1/2 substrates.