Inhibition of HeLa cell toxicity by attenuated <i>Y. pestis</i> in the presence of selected small molecule inhibitors.

The HeLa cells were incubated with attenuated Y. pestis KIM19 strain in the presence of small molecules in DMEM medium supplemented with 10% FBS as described under Materials and Methods. Cell toxicity was scored by calculating the percentage of rounded versus the squamous cells under a microscope. Only data for molecules showing 10% or more inhibition of cell rounding at 50 µM inhibitor concentration are shown.