The Cancer Dependency Map (DepMap)

The Cancer Dependency Map (DepMap) aims to accelerate precision cancer medicine by creating a comprehensive map of tumor vulnerabilities. The DepMap project genomically profiles a wide range of cancer models and characterizes them for their sensitivity to genetic and compound perturbations. The data is computationally analyzed to create a systematic overview of the genetic dependencies and compound sensitivities of cancer types and the predictive biomarkers that point to patient populations most likely to benefit from targeting of these vulnerabilities. The DepMap public portal has become a comprehensive resource to identify cancer vulnerabilities by providing datasets at scale, cutting-edge computational tools, and sophisticated visualization tools that together have accelerated the discovery of novel targets and biomarkers. Please visit Depmap.org to access the public portal. ]]>
Version 1: This dataset contains whole genome sequencing and RNA-Seq data generated by the DepMap project for 341 cell lines available on DepMap.org. Please note, data is added to this project on a rolling basis and will create a new version.Version 2: This dataset contains whole genome sequencing and RNA-Seq data generated by the DepMap project for 41 additional cell lines available on DepMap.org. Please note, data is added to this project on a rolling basis and will create a new version.Version 3: This dataset contains whole genome sequencing and RNA-Seq data generated by the DepMap project for 126 additional cell lines available on DepMap.org. Please note, data is added to this project on a rolling basis and will create a new version.]]>