Background: Deletion of 1p is associated with poor prognosis in neuroblastoma, however selected 1p-intact patients still experience poor outcomes. Since mutations of 1p genes may mimic the deleterious
Retinoblastoma is a pediatric cancer of the developing retina. All retinoblastomas are believed to initiate with biallelic inactivation of the RB1 gene. To identify subsequent genetic lesions in retin
Comparative analysis of H3K9me3 and H3K27me3 in RB1 KO and wild type IMR-90 cells Overall design: Examination of 2 histone modifications in RB1 KO and wild type IMR-90 cells
a Minor allele/major alleleb Significant results after multiple correction are in boldRisk alleles associated with neuroblastoma in Chinese children revealed by logistic regression analysis with adjus