Ruthenium-Catalyzed Synthesis of Fused Tricyclic 1H‑2,3-Dihydropyrimido[1,2‑a]quinolines in One Step
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A novel ruthenium-catalyzed intramolecular cyclization of a nitrile and an azetidine was developed to achieve a one-step synthesis of the fused tricyclic 1H-2,3-dihydropyrimido[1,2-a]quinoline, which is the core skeleton for more than 100 natural pyoverdines and is also responsible for their fluorescence.
创建时间:
2017-06-23




