Plant Co-expression Annotation Resource

he Plant Co-expression Annotation Resource, or plantannot in short, is a system developed to find proteins that have no annotation or function assigned (PUFs, or Proteins of Unknown Function) and could be related to molecular mechanisms regarding abiotic stresses in plants. The systems aggregates orthology, coexpression networks and genomic data to filter the genomes of 53 plants (downloaded from Phytozome and NCBI) and select candidate proteins in that regard.植物共表达注释资源（Plant Co-expression Annotation Resource，简称plantannot）是一套旨在挖掘未被注释或未赋予功能、且可能与植物非生物胁迫相关分子机制存在关联的蛋白质（未知功能蛋白质，Proteins of Unknown Function，简称PUFs）的系统。该系统整合直系同源（orthology）数据、共表达网络及基因组数据，对从Phytozome和NCBI下载的53种植物的基因组进行筛选，以此选出该研究方向下的候选蛋白质。

搜集汇总

背景与挑战

背景概述

Plant Co-expression Annotation Resource（简称plantannot）是一个旨在通过整合正交组、共表达网络和基因组数据，从67种植物中筛选与非生物胁迫相关的未知功能蛋白（PUFs）的系统。该系统利用共关联算法，通过已知注释的蛋白质来推断PUFs的功能，并基于RNA-seq数据构建了四种模式植物的共表达网络以支持分析。