Under Normoxia Simvastatin Shifts Lipid Metabolism of B16.F10 Melanoma Cells to Support Their Aggressiveness

Supplementary data to paper: "Under Normoxia Simvastatin Shifts Lipid Metabolism of B16.F10 Melanoma Cells to Support Their Aggressiveness" by Negrea et al., 2024.
These data represent: 1) the Supplementary Table corresponding to all the mRNA identified by RNA-seq in B16.F10 melanoma cells treated with lipophilic statin simvastatin (SIM), compared to the untreated cells. Our data revealed a panel of 1512 out of 15905 transcripts with at least 1.5 FR in expression after SIM treatment, with 816 transcripts upregulated, and 696 downregulated compared to the control group; 2) Figure 1. Validation of primer specificity by agarose electrophoresis of PCR products; 3) Figure 2. Relative expression of genes involved in metabolic pathways assessed by RT-qPCR; 4) Supplementary Table 2. GO and KEGG analysis results; 5) Supplementary Table 3. PPI data; 6) Supplementary Table 4. DEGs related to Aggresiveness.