*N = 26 rats. Data reported as mean ± SD. Abbreviations: CKD, chronic kidney disease; PTX+CKD, parathyroidectomy and chronic kidney disease; MS/BS, percent mineralized bone surface; MAR, mineral appos
Introduction: Experimental studies have suggested that indoxyl sulfate (IS), a protein-bound uremic toxin, may be involved in the development of renal osteodystrophy. Objective: evaluate the associati
The pathogenesis of renal osteopathy and cardiovascular disease suggests the disordered bone–vessel axis in chronic kidney disease–mineral bone disorder (CKD–MBD). However, the mechanism of the bone–v
Inflammation plays a major role in the pathogenesis of chronic kidney disease (CKD), but the relationship between systemic inflammation and CKD-mineral bone disease is unclear. We aimed to investigate
