Brain regions that showed significant deactivation during passive right hand movement within each of the three groups.

L = left; R = Right; Bi = Bilateral; MNI = Montreal Neurological Institute.HC = Healthy Controls; RRMS = Relapsing Remitting MS patients; SPMS = Secondary Progressive MS patients; n.s. = not statistically significant.Results obtained from a one-sample t-test after correcting for age, p