Cryo-EM structure of RET/GFRa3/ARTN extracellular complex. The 3D refinement was applied with C2 symmetry.

Cryo-EM structure of RET/GFRa3/ARTN extracellular complex. The 3D refinement was applied with C2 symmetry. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-3, ... Authors: Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. Deposit date: 2019-08-08 Release date: 2019-10-02 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019

RET/GFRα3/ARTN 细胞外复合物的冷冻电镜（Cryo-EM）结构。该结构采用C2对称性进行三维重构精修。组分描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、钙离子、胶质细胞源性神经营养因子家族受体α3（GDNF family receptor alpha-3）等。作者：Li, J、Shang, G.J、Chen, Y.J、Brautigam, C.A、Liou, J、Zhang, X.W、Bai, X.C。提交日期：2019年8月8日；发布日期：2019年10月2日；最后更新：2024年10月23日。研究方法：电子显微技术（分辨率3.8埃）。引用文献：《冷冻电镜分析揭示不同配体激活RET的共同机制与分化模式》，《Elife》，第8卷，2019年。