Interactive effects of ZnO nanoparticles and temperature on molecular and cellular stress responses of the blue mussel Mytilus edulis

We investigate the molecular and cellular stress responses of tissues (gills and digestive glands) in the mussels <em>Mytilus edulis </em>exposed for 21 days to either ambient (10 °C in winter and 15 °C in summer) or elevated (by 5 °C) temperature combined with different concentrations (0, 10, 100 µg l^-1) of ZnO nanoparticles or dissolved zinc. In this data set, we used a biomarker-based approach focusing on oxidative stress indicators ( lipid peroxidation and protein carbonyls) and transcription pattern of marker genes in the pathways related to cell survival and proliferation (caspase 3, Bcl-2, p53, p38 and JNK) and inflammation (COX, NF-κB, and TGF-β) of <em>M. edulis</em>.