Transcription profiling of Escherichia coli K-12 WT and deletion mutants (del.yhdN, del.yeaC and del.ydgH)

This study investigates the transcriptional response of Escherichia coli K-12 BW25113 to two distinct stress conditions: heat shock and oxidative stress. The experiment includes wild-type (WT) E. coli K-12, a yhdN mutant under heat shock conditions (50 degree celsius for 7 minutes), yeaC and ydgH mutants under oxidative stress induced by hydrogen peroxide (2.5 mM). RNA sequencing was performed to capture the global transcriptional changes in response to these stressors. The data generated provides insights into the gene expression profiles and regulatory mechanisms employed by E. coli K-12 and its mutants to cope with environmental stress, contributing to our understanding of bacterial stress responses and resilience. This dataset includes raw RNA-seq reads, processed data, and associated metadata.