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ENHANCED INTERFERON-SENSING BY AGGRESSIVE CHRONIC LYMPHOCYTIC LEUKEMIA CELLS

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE196741
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Purpose: to determine the CLL-B cells' interferome Methods: CLL cells from 3 of the patients previously classified as responders were purified and treated with anifrolumab in vitro and RNA was analyzed by RNAseq. Gene expression in purified CLL cells before and 24h after treatment with anifrolumab at 9.25ug/ml in vitro were compared by RNAseq.
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2023-06-25
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