Npy2r
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1551786
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资源简介:
Enables peptide YY receptor activity. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in non-motile cilium. Is active in cilium. Is expressed in central nervous system; dorsal root ganglion; eye; and metanephros. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (neuropeptide Y receptor Y2). [provided by Alliance of Genome Resources, Nov 2024]
本数据集所描述的肽YY受体活性得以激活。位于腺苷酸环化酶抑制型G蛋白偶联受体信号通路的上游或其中。该受体定位于非移动纤毛上,并在纤毛中保持活性。其在中枢神经系统、背根神经节、眼球和后肾中表达。人类本基因的同源基因与亨廷顿病、病态肥胖和肥胖有关。与人类NPY2R(神经肽Y受体Y2)同源。[由基因组资源联盟提供,2024年11月]
提供机构:
Rat Genome Database



