Genome-wide identification of direct HBx targets that control HBV replication
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https://www.ncbi.nlm.nih.gov/sra/ERP014776
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资源简介:
The Hepatitis B Virus HBx regulatory protein is required for HBV replication and implicated in HBV-related carcinogenesis. HBx interacts with chromatin modifying enzymes and transcription factors to modulate histone post-translational modifications and to regulate viral cccDNA transcription and cellular gene expression. To identify genes and ncRNAs directly targeted by HBx, we performed a ChIP-Seq analysis of HBx chromatin recruitment in HBV replicating cells.
创建时间:
2018-02-21



